Gene Expression Databases and Data Mining
نویسندگان
چکیده
منابع مشابه
Gene expression databases and data mining.
The DNA microarray technology has arguably caught the attention of the worldwide life science community and is now systematically supporting major discoveries in many fields of study. The majority of the initial technical challenges of conducting experiments are being resolved, only to be replaced with new informatics hurdles, including statistical analysis, data visualization, interpretation, ...
متن کاملMining gene expression databases for association rules
MOTIVATION Global gene expression profiling, both at the transcript level and at the protein level, can be a valuable tool in the understanding of genes, biological networks, and cellular states. As larger and larger gene expression data sets become available, data mining techniques can be applied to identify patterns of interest in the data. Association rules, used widely in the area of market...
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Micro-array data has enabled us to obtain an overview of the cell by measuring the expression levels of thousands of genes simultaneously. It has also opened the possibility for predicting possible cancerous cells accurately. Since these data sets are very large, we need to utilize machine learning techniques to analyse them efficiently. However, micro-array data also poses challenging problems...
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DNA microarray technology provides biologists with the ability to measure the expression levels of thousands of genes in a single experiment. Many initial experiments suggest that genes of similar function yield similar expression patterns in microarray hybridization experiments. Hence it makes possible to distinguish genes with different functions by analyzing gene data generated from microarr...
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Gene expression databases contain a wealth of information, but current data mining tools are limited in their speed and effectiveness in extracting meaningful biological knowledge from them. Online analytical processing (OLAP) can be used as a supplement to cluster analysis for fast and effective data mining of gene expression databases. We used Analysis Services 2000, a product that ships with...
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ژورنال
عنوان ژورنال: BioTechniques
سال: 2003
ISSN: 0736-6205,1940-9818
DOI: 10.2144/mar03anderle